Proteintech, 68456-1-Ig, EXOSC7 Monoclonal antibody

Size: 20ul / 150ul The EXOSC7 (68456-1-Ig) by Proteintech is a Monoclonal antibody targeting EXOSC7 in WB, ELISA applications with reactivity to human, mouse, rat, pig, rabbit samples 68456-1-Ig targets EXOSC7 in WB, ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples. Tested Applications Positive WB detected in: Saos-2 cells, HSC-T6 cells, PANC-1 cells, NIH/3T3 cells, 4TA cells, HT-29 cells, LNCaP cells, MDA-MB-231 cells, IMR-32 cells, rat brain tissue, mouse brain tissue, rabbit brain tissue, pig brain tissue, Caco-2 cells, HeLa cells, HEK-293 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. EXOSC7 also named as RRP42 or EAP1 is a 291 amino acid protein, which belongs to the RNase PH family. EXOSC7 is one of the six RNase-PH domain subunits of the exosome and required for the processing of the 7S pre-RNA. Specification Tested Reactivity: human, mouse, rat, pig, rabbit Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag18322 Product name: Recombinant human EXOSC7 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-291 aa of BC012831 Sequence: MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMETGKRVGKVLHASLQSVLHKEESLGPKRQKVGFLG Predict reactive species Full Name: exosome component 7 Calculated Molecular Weight: 291 aa, 32 kDa Observed Molecular Weight: 35 kDa GenBank Accession Number: BC012831 Gene Symbol: EXOSC7 Gene ID (NCBI): 23016 RRID: AB_3085168 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q15024 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.