Proteintech, 68516-1-Ig, ATL3 Monoclonal antibody

Size: 20ul / 150ul The ATL3 (68516-1-Ig) by Proteintech is a Monoclonal antibody targeting ATL3 in WB, IF/ICC, ELISA applications with reactivity to human, mouse, rat, rabbit samples 68516-1-Ig targets ATL3 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples. Tested Applications Positive WB detected in: PC-3 cells, Jurkat cells, HeLa cells, K-562 cells, rabbit testis tissue, rat testis tissue, mouse testis tissue Positive IF/ICC detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunofluorescence (IF)/ICC: IF/ICC : 1:500-1:2000 Background Information ATL3, belonging to a class of dynamin-like GTPase, was reported to mediate ER fusion. ATL3 is required for the proper formation of the network of interconnected tubules of the endoplasmic reticulum. ATL3 functions as a receptor for ER-phagy, promoting tubular ER degradation upon starvation. Mutations in this gene may be associated with hereditary sensory neuropathy type IF. Specification Tested Reactivity: human, mouse, rat, rabbit Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Immunogen: CatNo: Ag10248 Product name: Recombinant human ATL3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-351 aa of BC077727 Sequence: MLSPQRVAAAASRGADDAMESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKSFILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGKKVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRLAMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIHSCFSDVTCFLLPHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLLEYFKAYIKIYQGEDLPHPKSMLQATAEAN Predict reactive species Full Name: atlastin GTPase 3 Calculated Molecular Weight: 541 aa, 61 kDa Observed Molecular Weight: 61 kDa GenBank Accession Number: BC077727 Gene Symbol: ATL3 Gene ID (NCBI): 25923 RRID: AB_3085225 Conjugate: Unconjugated Form: Liquid Purification Method: Protein G purification UNIPROT ID: Q6DD88 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.