Proteintech, 68538-1-Ig, 4-Hydroxynonenal Monoclonal antibody

Size: 20ul / 150ul The 4-Hydroxynonenal (68538-1-Ig) by Proteintech is a Monoclonal antibody targeting 4-Hydroxynonenal in ELISA applications with reactivity to 4-hydroxynonenal, chemical compound samples 68538-1-Ig targets 4-Hydroxynonenal in WB, IHC, IF, ELISA applications and shows reactivity with 4-hydroxynonenal, chemical compound samples. Tested Applications Positive ELISA detected in: 4-Hydroxynonenal Recommended dilution Enzyme-linked Immunosorbent Assay (ELISA): ELISA : 1:5000-1:20000 Background Information 4-Hydroxynonenal is a uremic toxin. Uremic toxins can be subdivided into three major groups based upon their chemical and physical characteristics: 1) small, water-soluble, non-protein-bound compounds, such as urea; 2) small, lipid-soluble and/or protein-bound compounds, such as the phenols and 3) larger so-called middle-molecules, such as beta2-microglobulin. 4-Hydroxynonenal (4-HNE) is a major aldehydic product of ω-6-unsaturated fatty acid peroxidation. It is considered a lipid peroxidation specific marker. 4-HNE has been found to induce differentiation and inhibit proliferation of HL-60 human leukemic cells. It has also been found to induce murine alveolar macrophage cell death. 4-HNE has been shown to inhibit State 3 respiration, causing a transient cytosolic Ca2+ increase. In addition, it irreversibly inhibits Na+-K+-ATPase activity. Specification Tested Reactivity: 4-hydroxynonenal, chemical compound Cited Reactivity: mouse, rat Host / Isotype: Mouse / IgG2a Class: Monoclonal Type: Antibody Immunogen: PTG Predict reactive species Full Name: 4-Hydroxynonenal RRID: AB_3085246 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.