Proteintech, 69033-1-Ig, NeutraKine®M-CSF Monoclonal antibody

Size: 25ug / 100ug The NeutraKine®M-CSF (69033-1-Ig) by Proteintech is a Monoclonal antibody targeting NeutraKine®M-CSF in ELISA, Neutralization applications with reactivity to Human samples 69033-1-Ig targets NeutraKine®M-CSF in ELISA, Neutralization applications and shows reactivity with Human samples. Background Information M-CSF plays an essential role in the regulation of survival, proliferation, and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes. M-CSF promotes the release of proinflammatory chemokines and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. On the cellular level, M-CSF promotes reorganization of the actin cytoskeleton, regulates the formation of membrane ruffles, cell adhesion, and cell migration, and plays a role in lipoprotein clearance.This antibody is used to neutralize the bioactivity of M-CSF. Specification Tested Reactivity: Human Host / Isotype: Mouse / IgG1 Class: Monoclonal Type: Antibody Affinity: K D =8.48 x 10 -9 M K Off =4.75 x 10 -4 M K On =5.60 x 10 4 M Immunogen: RecombinantProtein Predict reactive species Full Name: colony stimulating factor 1 (macrophage) Gene Symbol: M-CSF Gene ID (NCBI): 1435 RRID: AB_3085334 Conjugate: Unconjugated Form: Lyophilized Powder Purification Method: Protein G purification UNIPROT ID: P09603 Storage Buffer: Sterile PBS, pH 7.4. Endotoxin: <0.1 EU/μg Reconstitution: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. Stability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.