Product Description
Size: 100ug
The NeutraControl SCF (69530-1-Ig) by Proteintech is a Monoclonal antibody targeting NeutraControl SCF in ELISA, Non-Neutralization applications with reactivity to Human samples
69530-1-Ig targets SCF in ELISA, Non-Neutralization applications and shows reactivity with Human samples.
Background Information
Stem cell factor (SCF) also known as mast cell growth factor, steel factor, and kit ligand, is a hematopoietic growth factor. SCF is a critical protein with key roles in the cell such as hematopoiesis, gametogenesis and melanogenesis. SCF activates multiple signal pathways by binding with c-kit receptor. SCF and its receptor, c-kit ligand (KL), are up-regulated in particular human malignancies including gastrointestinal stromal tumor (GISTs), breast cancer, hematopoietic cell, myeloid leukaemia, and glioma. The SCF/c-KIT system also plays a relevant role in cell fate decision, and its activity is widely known to control cell proliferation, differentiation, survival and apoptosis.This antibody is a neutralizing control antibody for SCF, the immunogen is the same as Neutrakine 69030-1-Ig but could not neutralize human SCF.
Specification
Tested Reactivity: Human
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Immunogen: CatNo: Product name: HumanKine® recombinant human SCF protein Source: -derived, Tag: Domain: of Sequence: Predict reactive species
Full Name: KIT ligand
Gene Symbol: SCF
Gene ID (NCBI): 4254
RRID: AB_2935404
Conjugate: Unconjugated
Form: Lyophilized Powder
Purification Method: Protein G purification
UNIPROT ID: P21583
Storage Buffer: Sterile PBS, pH 7.4.
Endotoxin: <0.1 EU/μg
Reconstitution: This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and Storage: Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.
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Collaboration
Tony Tang
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