Proteintech, 80137-1-RR, MAP2K3 Recombinant monoclonal antibody

Size: 20ul / 100ul The MAP2K3 (80137-1-RR) by Proteintech is a Recombinant antibody targeting MAP2K3 in WB, IF/ICC, ELISA applications with reactivity to human, mouse, rat, zebrafish samples 80137-1-RR targets MAP2K3 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat, zebrafish samples. Tested Applications Positive WB detected in: Jurkat cells, A431 cells, C6 cells, HepG2 cells, HT-1080 cells, zebrafish tissue, C2C12 cells, NIH/3T3 cells, HeLa cells, HEK-293 cells Positive IF/ICC detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800 Background Information MAP2K3, also named MKK3, is a member of dual specificity kinase group and serves as a specific activator of p38 MAPK with MKK6. MKK3 can be phosphorylated by cytokines and environmental stress at sites Ser189 and Thr193 by MKKK proteins (MEKK 1-4). MKK3 plays a key role in cell differentiation, motility, division and death. It has been reported that MKK3 targeting may represent an effective and potentially safe therapeutic strategy to selectively kill cancer cells in colorectal cancer patients. (PMID: 31695024, 30770795, 26805700, 8622669) Specification Tested Reactivity: human, mouse, rat, zebrafish Cited Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: mitogen-activated protein kinase kinase 3 Calculated Molecular Weight: 347 aa, 39 kDa Observed Molecular Weight: 39 kDa GenBank Accession Number: BC032478 Gene Symbol: MAP2K3 Gene ID (NCBI): 5606 RRID: AB_2918868 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P46734 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.