Proteintech, 81363-2-RR, Phospho-TBC1D1 (Ser660) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-TBC1D1 (Ser660) (81363-2-RR) by Proteintech is a Recombinant antibody targeting Phospho-TBC1D1 (Ser660) in WB, ELISA applications with reactivity to human, mouse samples 81363-2-RR targets Phospho-TBC1D1 (Ser660) in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: Calyculin A treated NIH/3T3 cells, Calyculin A treated HeLa cells Recommended dilution Western Blot (WB): WB : 1:2000-1:5000 Background Information TBC1D1 belong to the family of RabGAPs and its physiological roles in glucose homeostasis and its implication in human diseases have already been characterized in skeletal muscle and adipocytes in a large number of independent studies. TBC1D1 including twophospho-tyrosine-binding (PTB) domains, a calmodulin-binding domain(CBD) and the func-tional GAP domain responsible for catalyzing GTP hydrolysis. TBC1D1 is phosphorylated by AMPK at Ser660 and Thr237, and by AKT at Thr596. The RabGAPs TBC1D1 is important regulators of glucose homeostasis inskeletal muscle and adipose tissue. (PMID: 31627187, PMID: 18477703) Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 Calculated Molecular Weight: 133 kDa Observed Molecular Weight: 160 kDa GenBank Accession Number: BC050321 Gene Symbol: TBC1D1 Gene ID (NCBI): 23216 RRID: AB_3085355 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q86TI0 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.