Proteintech, 83068-5-RR, IFNAR2 Recombinant monoclonal antibody

Size: 20ul / 100ul The IFNAR2 (83068-5-RR) by Proteintech is a Recombinant antibody targeting IFNAR2 in WB, IF/ICC, ELISA applications with reactivity to human samples 83068-5-RR targets IFNAR2 in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: U266 cells, HeLa cells, MCF-7 cells Positive IF/ICC detected in: U266 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500 Background Information Interferon alpha/beta receptor 2 (IFNAR2) is a type I membrane protein that associates with IFNAR1 to form the receptor for type I interferons. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2928 Product name: Recombinant Human IFNAR2 protein (rFc Tag) (HPLC verified) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 27-243 aa of NM_207585.2 Sequence: ISYDSPDYTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAK Predict reactive species Full Name: interferon (alpha, beta and omega) receptor 2 Calculated Molecular Weight: 58 kDa Observed Molecular Weight: 90-100 kDa GenBank Accession Number: NM_207585.2 Gene Symbol: IFNAR2 Gene ID (NCBI): 3455 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P48551-1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.