Proteintech, 83165-3-RR, Angiopoietin-like 3/ANGPTL3 Recombinant monoclonal antibody

Size: 20ul / 100ul The Angiopoietin-like 3/ANGPTL3 (83165-3-RR) by Proteintech is a Recombinant antibody targeting Angiopoietin-like 3/ANGPTL3 in WB, ELISA applications with reactivity to Human samples 83165-3-RR targets Angiopoietin-like 3/ANGPTL3 in WB, ELISA applications and shows reactivity with Human samples. Tested Applications Positive WB detected in: HepG2 cells, A375 cells, HEK-293 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information ANGPTL3 belongs to the angiopoietin-like protein family. ANGPTL3 is mainly synthesized by liver cells and is notably expressed in kidney podocytes. Accumulating evidences have revealed that ANGPTL3 plays a critical role in both biological processes, such as lipid metabolism, angiogenesis and haematopoietic function and pathological changes, including atherosclerosis, carcinogenesis, nephrotic syndrome, diabetes, liver diseases and so on. Thus, ANGPTL3 may serve as a potential biomarker in these diseases. ANGPTL3 belongs to a multifunctional secreted protein that mainly expresses in the liver, and is regulated by numerous post-translational modifications, including multiple cleavage and glycosylation (PMID: 30615486). Specification Tested Reactivity: Human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Fusion Protein Predict reactive species Full Name: angiopoietin-like 3 Calculated Molecular Weight: 53KD Observed Molecular Weight: 54 kDa, 70 kDa GenBank Accession Number: NM_013913.4 Gene Symbol: Angptl3 Gene ID (NCBI): 30924 RRID: AB_3670860 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q9R182 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.