Proteintech, 83781-4-RR, IL-21 Recombinant monoclonal antibody

Size: 20ul / 100ul The IL-21 (83781-4-RR) by Proteintech is a Recombinant antibody targeting IL-21 in WB, ELISA applications with reactivity to human samples 83781-4-RR targets IL-21 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Recombinant protein, Transfected with Human IL21 CHO cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Interleukin 21 (IL-21) is a cytokine produced predominantly by cluster of differentiation 4 (CD4+) T-cells and natural killer T-cells. IL-21 is preliminarily expressed in activated cluster of differentiation 4 (CD4+) T-cells and natural killer (NK) T-cells. IL-21 receptor (IL-21R) is a class I cytokine receptor, which requires dimerization with the indispensable common gamma chain (γc) subunit to bind IL-21. IL-21 plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. IL-21 mediates apoptosis in B-CLL cells through up-regulation of the BIM (BH3 family member) and enhances both direct and antibody-dependent cellular cytotoxicity in these cells. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Product name: HumanKine® recombinant human IL-21 protein Source: -derived, Tag: Domain: of Sequence: Predict reactive species Full Name: interleukin 21 Calculated Molecular Weight: 162 aa, 19 kDa GenBank Accession Number: BC066258 Gene Symbol: IL-21 Gene ID (NCBI): 59067 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9HBE4 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.