Proteintech, 83907-5-RR, CD83 Recombinant monoclonal antibody

Size: 20ul / 100ul The CD83 (83907-5-RR) by Proteintech is a Recombinant antibody targeting CD83 in WB, ELISA applications with reactivity to human, mouse samples 83907-5-RR targets CD83 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: Raji cells, mouse spleen tissue, mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also be expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928). PNGase F (peptide N-glycosidase F) digestion reduced the 37 kDa and 50 kDa CD83 forms to 28 kDa (PMID: 15320871). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg10435 Product name: Recombinant mouse CD83 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 10011478 of Sequence: \ Predict reactive species Full Name: CD83 antigen Observed Molecular Weight: 50 kDa Gene Symbol: Cd83 Gene ID (NCBI): 12522 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O88324 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.