Proteintech, 83918-3-RR, IL-23R Recombinant monoclonal antibody

Size: 20ul / 100ul The IL-23R (83918-3-RR) by Proteintech is a Recombinant antibody targeting IL-23R in WB, ELISA applications with reactivity to human, mouse samples 83918-3-RR targets IL-23R in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: K-562 cells, Jurkat cells, RAW 264.7 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information Interleukin-23 receptor (IL-23R) is a type I cytokine receptor that plays a critical role in immune responses and inflammation. It forms a receptor complex with IL-12Rβ1 and is activated by the cytokine IL-23, which is primarily produced by dendritic cells and activated macrophages (PMID: 39796684). The genetic and epigenetic interactions in the IL-23R/IL-17 axis are associated with elevated expression of IL-17 and inflammatory bowel disease (IBD) pathogenesis (PMID: 21672939). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: interleukin 23 receptor Calculated Molecular Weight: 73 kDa Observed Molecular Weight: 73 kDa Gene Symbol: Il23r Gene ID (NCBI): 209590 RRID: AB_3671497 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q8K4B4 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.