Proteintech, 84043-1-RR, NPR1 Recombinant monoclonal antibody

Size: 20ul / 100ul The NPR1 (84043-1-RR) by Proteintech is a Recombinant antibody targeting NPR1 in WB, IF/ICC, ELISA applications with reactivity to human samples 84043-1-RR targets NPR1 in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HT-29 cells, HeLa cells, SGC-7901 cells Positive IF/ICC detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800 Background Information NPR1(Atrial natriuretic peptide receptor 1), also named as NPRA , is a transmembrane protein expressed in the vascular endothelium. Activation of NPRA requires a binding of natriuretic peptides NPPA (ANP) or NPPB (BNP) to its extracellular domain and this promotes the production of cyclic guanosine monophosphate (cGMP), which in turn activates protein kinase cGMP‐dependent 1 (PRKG1 or commonly used as PKG). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) Calculated Molecular Weight: 119 kDa Observed Molecular Weight: 119-125 kDa GenBank Accession Number: NM_000906 Gene Symbol: NPR1 Gene ID (NCBI): 4881 RRID: AB_3671610 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P16066 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.