Product Description
Size: 20ul / 100ul
The SRP19 (84061-3-RR) by Proteintech is a Recombinant antibody targeting SRP19 in WB, IF/ICC, ELISA applications with reactivity to human, mouse samples
84061-3-RR targets SRP19 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: HeLa cells, A549 cells, K-562 cells, Raji cells, mouse kidney tissue, mouse ovary tissue, mouse liver tissue
Positive IF/ICC detected in: HeLa cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500
Background Information
The signal recognition particle (SRP) is one of the few functional small RNP particles. The SRP couples the synthesis of membrane and secretory proteins across or into the endoplasmic reticulum (ER) membrane in eukaryotes, as well as across the bacterial plasma membrane, and chloroplast thylakoid membranes. The mammalian SRP is composed of a 7S (or 7SL) RNA and six different proteins, SRP9, SRP14, SRP19, SRP54, SRP68 and SRP72. All of the components of SRP, including SRP RNA, participate directly in the overall protein targeting process. SRP19 binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. SRP19 was shown to significantly enhance SRP54 attachment to helix 8 of 7SL RNA.
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag8903 Product name: Recombinant human SRP19 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-144 aa of BC010947 Sequence: MACTAARSPADQDRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNVFLEKNKMYSREWNRDVQYRGRVRVQLKQEDGSLCLVQFPSRKSVMLYAAEMIPKLKTRTQKTGGADQSLQQGEGSKKGKGKKKK Predict reactive species
Full Name: signal recognition particle 19kDa
Calculated Molecular Weight: 144 aa, 16 kDa
Observed Molecular Weight: 17 kDa
GenBank Accession Number: BC010947
Gene Symbol: SRP19
Gene ID (NCBI): 6728
RRID: AB_3671631
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purfication
UNIPROT ID: P09132
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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