Proteintech, 84274-1-RR, IL-1 beta Recombinant monoclonal antibody

Size: 20ul / 100ul The IL-1 beta (84274-1-RR) by Proteintech is a Recombinant antibody targeting IL-1 beta in WB, ELISA applications with reactivity to rat samples 84274-1-RR targets IL-1 beta in WB, ELISA applications and shows reactivity with rat samples. Tested Applications Positive WB detected in: LPS and Brefeldin A treated NR8383 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets. Specification Tested Reactivity: rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: interleukin 1 beta Calculated Molecular Weight: 31 kDa Observed Molecular Weight: 31 kDa GenBank Accession Number: NM_031512 Gene Symbol: IL-1 beta Gene ID (NCBI): 24494 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q63264 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.