Proteintech, 84295-3-RR, P glycoprotein Recombinant monoclonal antibody

Size: 20ul / 100ul The P glycoprotein (84295-3-RR) by Proteintech is a Recombinant antibody targeting P glycoprotein in WB, ELISA applications with reactivity to human samples 84295-3-RR targets P glycoprotein in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: PC-3 cells, HuH-7 cells, HepG2 cells, HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1 Calculated Molecular Weight: 1280 aa, 142 kDa Observed Molecular Weight: 130-150 kDa GenBank Accession Number: BC130424 Gene Symbol: P glycoprotein Gene ID (NCBI): 5243 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P08183 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.