Proteintech, 84321-3-RR, CLUH Recombinant monoclonal antibody

Size: 20ul / 100ul The CLUH (84321-3-RR) by Proteintech is a Recombinant antibody targeting CLUH in WB, ELISA applications with reactivity to human, mouse samples 84321-3-RR targets CLUH in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: HeLa cells, HEK-293T cells, A549 cells, HCT 116 cells, mouse tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Clustered mitochondria homolog (CLUH) is a conserved RNA-binding protein, that binds transcripts encoding proteins involved in the respiratory chain, the tricarboxylic acid (TCA) cycle, and other mitochondrial metabolic pathways. Upon loss of CLUH, target mRNAs are subjected to faster decay, and their respective proteins are decreased in abundance. This leads to alterations in mitochondrial distribution (mitochondrial clustering as the gene name alludes to) mitochondrial cristae integrity, respiratory defects, loss of mtDNA, and decreased activity of TCA cycle enzymes. (PMID: 35559794) Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag34275 Product name: Recombinant human CLUH protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1120-1309 aa of BC156940 Sequence: YDLSLRFLENALAVSTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEASRNRDRAEEPMATEPAPAGAPGDLGSQPPAAKDPSPSVQG Predict reactive species Full Name: KIAA0664 Observed Molecular Weight: 147-150 kDa GenBank Accession Number: BC156940 Gene Symbol: CLUH Gene ID (NCBI): 23277 RRID: AB_3671862 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: O75153 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.