Product Description
Size: 20ul / 100ul
The ORAI3 (84340-2-RR) by Proteintech is a Recombinant antibody targeting ORAI3 in WB, IF/ICC, ELISA applications with reactivity to human samples
84340-2-RR targets ORAI3 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: Jurkat cells, MCF-7 cells, A549 cells
Positive IF/ICC detected in: Jurkat cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800
Background Information
ORAI3, also named TMEM142C, is a key regulator or component of store-operated Ca2+ channels and transcription factor NFAT nuclear import. ORAI3 channels appeared to differ from Orai1 and -2 in being somewhat resistant to Ca2+ depotentiation. The molecular weight of monomers and dimers for Orai3 is about 30-35 kDa and 60-70 kDa (PMID: 20971921; 17293345; 22580508).
Specification
Tested Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Ag36135 Product name: Recombinant human ORAI3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-100 aa of BC006126 Sequence: MKGGEGDAGEQAPLNPEGESPAGSATYREFVHRGYLDLMGASQHSLRALSWRRLYLSRAKLKASSRTSALLSGFAMVAMVEVQLESDHEYPPGLLVAFSA Predict reactive species
Full Name: ORAI calcium release-activated calcium modulator 3
Calculated Molecular Weight: 295 aa, 32 kDa
Observed Molecular Weight: ~30 kDa,~60 kDa
GenBank Accession Number: BC006126
Gene Symbol: ORAI3
Gene ID (NCBI): 93129
RRID: AB_3671881
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: Q9BRQ5
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
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