Proteintech, 84391-4-RR, IL-12RB1/CD212 Recombinant monoclonal antibody

Size: 20ul / 100ul The IL-12RB1/CD212 (84391-4-RR) by Proteintech is a Recombinant antibody targeting IL-12RB1/CD212 in IF/ICC, ELISA applications with reactivity to human samples 84391-4-RR targets IL-12RB1/CD212 in IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive IF/ICC detected in: K-562 cells, THP-1 cells Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500 Background Information IL12RB1, also named as Interleukin-12 receptor subunit beta-1 or CD212, is a 662 amino acid protein, which contains 5 fibronectin type-III domains and belongs to the type I cytokine receptor family. Type 2 subfamily. IL12RB1 localizes in the membrane and functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: interleukin 12 receptor, beta 1 Calculated Molecular Weight: 662 aa, 73 kDa GenBank Accession Number: BC029121 Gene Symbol: IL12RB1 Gene ID (NCBI): 3594 RRID: AB_3671926 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P42701 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.