Proteintech, 84535-2-RR, IL-17RA Recombinant monoclonal antibody

Size: 20ul / 100ul The IL-17RA (84535-2-RR) by Proteintech is a Recombinant antibody targeting IL-17RA in WB, ELISA applications with reactivity to human samples 84535-2-RR targets IL-17RA in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: THP-1 cells, Jurkat cells, K-562 cells, MOLT-4 cells, U-937 cells, Raji cells, U2OS cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Interleukin-17 receptor A (IL17A) is a major effector cytokine of the innate and adaptive immune system and is involved in antimicrobial host defense and maintenance of tissue integrity. It has been shown that IL-17A is involved in the pathogenesis of asthma and allergy and regulates local immune and inflammatory processes in bone tissue and is involved in the onset and progression of osteoporosis. In addition to this, due to polymorphisms in the IL17RA gene, it leads to the development of Fanconi anemia. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2317 Product name: Recombinant Human IL-17RA protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 33-320 aa of BC011624 Sequence: LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPIPDYMPLW Predict reactive species Full Name: interleukin 17 receptor A Calculated Molecular Weight: 866 aa, 96 kDa Observed Molecular Weight: 100-130 kDa GenBank Accession Number: BC011624 Gene Symbol: IL17RA Gene ID (NCBI): 23765 RRID: AB_3672042 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q96F46 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.