Proteintech, 84623-7-RR, IDS Recombinant monoclonal antibody

Size: 20ul / 100ul The IDS (84623-7-RR) by Proteintech is a Recombinant antibody targeting IDS in IF/ICC, ELISA applications with reactivity to human samples 84623-7-RR targets IDS in IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive IF/ICC detected in: HeLa cells Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:125-1:500 Background Information Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag31132 Product name: Recombinant human IDS protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 160-312 aa of BC006170 Sequence: PSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQSTEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIRQREDVQALNISVPYGPIPVDFQEDQSSTGFRLKTSSTRKYK Predict reactive species Full Name: iduronate 2-sulfatase Calculated Molecular Weight: 312aa,35 kDa; 550aa,62 kDa GenBank Accession Number: BC006170 Gene Symbol: IDS Gene ID (NCBI): 3423 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P22304 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.