Proteintech, 84628-5-RR, CD244 Recombinant monoclonal antibody

Size: 20ul / 100ul The CD244 (84628-5-RR) by Proteintech is a Recombinant antibody targeting CD244 in WB, ELISA applications with reactivity to mouse, rat samples 84628-5-RR targets CD244 in WB, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: DC2.4 cells, RAW 264.7 cells, mouse thymus tissue, rat thymus tissue, mouse spleen tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information CD244, also known as SLAMF4 or 2B4, is a type I transmembrane glycoprotein belonging to the signaling lymphocyte activation molecule (SLAM) family. It consists of an extracellular segment with two immunoglobulin (Ig)-like domains, a transmembrane region, and a cytoplasmic domain containing tyrosine-based motifs (PMID: 9841922; 30546369). CD244 is present on natural killer (NK) cells, γδ T cells, a subset of CD8+ T cells, monocytes, basophils, dendritic cells, and myeloid-derived suppressor cells (MDSCs) (PMID: 30546369). It binds to CD48 with high affinity and transmits stimulatory or inhibitory signals that regulate immune function (PMID: 9841922; 18523281). Specification Tested Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg10438 Product name: Recombinant mouse CD244 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 10011475 of Sequence: \ Predict reactive species Full Name: CD244 natural killer cell receptor 2B4 Observed Molecular Weight: 65 kDa Gene Symbol: Cd244 Gene ID (NCBI): 18106 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.