Proteintech, 84639-2-RR, CXCR5 Recombinant monoclonal antibody

Size: 20ul / 100ul The CXCR5 (84639-2-RR) by Proteintech is a Recombinant antibody targeting CXCR5 in WB, ELISA applications with reactivity to human samples 84639-2-RR targets CXCR5 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Daudi cells, Raji cells, Ramos cells, Jurkat cells, K-562 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information Initially discovered in 1992 as Burkitt's lymphoma receptor 1, CXCR5 (chemokine receptor 5, also known as CD185) is a seven-transmembrane G protein-coupled receptor (GPCR) protein (PMID: 32994482). CXCR5 is essential for naïve B-cell migration to and maturation in the lymph nodes and spleen, as well as for cluster of differentiation 4 T-cell (TFH and TCM) homing and interaction with B cells (PMID: 21471443). Moreover, CXCR5 is involved in the regulation of neural stem cells (NSC) and neuronal regeneration in the mouse brain, neuronal differentiation, neurogenesis, gliogenesis, and synaptogenesis (PMID: 37460877). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: chemokine (C-X-C motif) receptor 5 Calculated Molecular Weight: 372 aa, 42 kDa Observed Molecular Weight: 33 kDa GenBank Accession Number: BC110352 Gene Symbol: CXCR5 Gene ID (NCBI): 643 RRID: AB_3672098 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P32302 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.