Proteintech, 84796-3-RR, CD83 Recombinant monoclonal antibody

Size: 20ul / 100ul The CD83 (84796-3-RR) by Proteintech is a Recombinant antibody targeting CD83 in WB, ELISA applications with reactivity to human samples 84796-3-RR targets CD83 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Raji cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information CD83 is a member of the immunoglobulin (Ig) superfamily, consisting of an extracellular V-type Ig-like domain, a transmembrane domain, and a cytoplasmic tail. CD83 is one of the most prominent markers for fully matured dendritic cells (DCs) (PMID: 17334966). It is also found on the surface of other activated hematopoietic cells, including lymphocytes, monocytes, macrophages, and neutrophils (PMID: 31231400; 17334966). CD83 regulates the maturation, activation, and homeostasis of numerous immune cells (PMID: 31231400; 32362900). CD83 can also expressed as a soluble form. Soluble CD83 can bind to DCs and inhibit their maturation (PMID: 17334966; 12403928). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD83 molecule Calculated Molecular Weight: 23 kDa Observed Molecular Weight: 40-45 kDa GenBank Accession Number: NM_004233.4 Gene Symbol: CD83 Gene ID (NCBI): 9308 ENSEMBL Gene ID: ENSG00000112149 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q01151 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.