Proteintech, 84923-5-RR, FANCA Recombinant monoclonal antibody

Size: 20ul / 100ul The FANCA (84923-5-RR) by Proteintech is a Recombinant antibody targeting FANCA in WB, ELISA applications with reactivity to human samples 84923-5-RR targets FANCA in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HeLa cells, COLO 320 cells, A549 cells, HEK-293 cells, Jurkat cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information FANCA, also named as FAA, FACA and FANCH, is DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCA may be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Defects in FANCA are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is specific to isoform1 of FANCA. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag2598 Product name: Recombinant human FANCA protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-297 aa of BC008979 Sequence: MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLEAVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQMFVLRGFQKNSDLRRTVEPEKMPQVAVDVLQRMLIFALDALAAGVQEESSTHKIVRC Predict reactive species Full Name: Fanconi anemia, complementation group A Calculated Molecular Weight: 163 kDa Observed Molecular Weight: 163 kDa GenBank Accession Number: BC008979 Gene Symbol: FANCA Gene ID (NCBI): 2175 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O15360 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.