Proteintech, 85168-1-RR, KIR2DL1/KIR2DL3 Recombinant monoclonal antibody

Size: 20ul / 100ul The KIR2DL1/KIR2DL3 (85168-1-RR) by Proteintech is a Recombinant antibody targeting KIR2DL1/KIR2DL3 in WB, ELISA applications with reactivity to human samples 85168-1-RR targets KIR2DL1/KIR2DL3 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Recombinant protein Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Killer cell immunoglobulin-like receptor 2DL1 (KIR2DL1, also known as CD158A and NKAT1) is an inhibitory receptor of NK cells, with β-arrestin 2 mediated recruitment of the tyrosine phosphatases SHP-1 and SHP-2 to KIR2DL1 and facilitated downstream inhibitory signaling (PMID: 18604210). The effector function of NK cells expressing KIR2DL1 or KIR2DS1 is highly influenced by genetic variability and is calibrated by co-expression of additional NK receptors and cognate HLA-C2 ligands (PMID: 31024561). This antibody can recognize KIR2DL1 and KIR2DL3. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 Calculated Molecular Weight: 39 kDa Observed Molecular Weight: 45 kDa, 70 kDa GenBank Accession Number: BC069344 Gene Symbol: KIR2DL1 Gene ID (NCBI): 3802 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P43626 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.