Proteintech, 85915-1-RR, PTPN2 Recombinant monoclonal antibody

Size: 20ul / 100ul The PTPN2 (85915-1-RR) by Proteintech is a Recombinant antibody targeting PTPN2 in WB, IF/ICC, ELISA applications with reactivity to human samples 85915-1-RR targets PTPN2 in WB, IF/ICC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: K-562 cells, HeLa cells, HepG2 cells, A549 cells, HL-60 cells, NIH/3T3 cells, mouse thymus tissue Positive IF/ICC detected in: HeLa cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunofluorescence (IF)/ICC: IF/ICC : 1:500-1:2000 Background Information PTPN2(Tyrosine-protein phosphatase non-receptor type 2) is also named as PTPT and belongs to the protein-tyrosine phosphatase family. It may modulate beta-cell apoptosis and/or local release of inflammatory mediators in the course of a viral infection by acting, at least in part, at the pancreatic beta-cell level(PMID: 19825843). This protein has some isoforms produced by alternative splicing with the molecular mass of 40-50 kDa. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag1709 Product name: Recombinant human PTPN2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-346 aa of BC016727 Sequence: MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSE Predict reactive species Full Name: protein tyrosine phosphatase, non-receptor type 2 Calculated Molecular Weight: 49 kDa Observed Molecular Weight: 45 kDa GenBank Accession Number: BC016727 Gene Symbol: PTPN2 Gene ID (NCBI): 5771 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P17706 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.