Proteintech, 86029-1-RR, Serpinc1 Recombinant monoclonal antibody

Size: 20ul / 100ul The Serpinc1 (86029-1-RR) by Proteintech is a Recombinant antibody targeting Serpinc1 in WB, IHC, ELISA applications with reactivity to mouse, rat samples 86029-1-RR targets Serpinc1 in WB, IHC, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: mouse serum, rat serum, mouse liver tissue Positive IHC detected in: mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunohistochemistry (IHC): IHC : 1:500-1:2000 Background Information SERPINC1 is a gene encoding antithrombin, also known as antithrombin III. The main function of antithrombin is to inhibit coagulation proteases such as thrombin and factor Xa, thereby preventing excessive coagulation and maintaining normal hemostasis and blood flow. Mutations in the SERPINC1 gene can lead to antithrombin deficiency (ATD), which is an autosomal dominant genetic disorder. The expression profile/molecular weight observed is consistent with what has been described in the literature (PMID: 3609301, PMID: 25485983, PMID: 35935621). Specification Tested Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg2949 Product name: Recombinant Mouse Serpinc1 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 33-465 aa of NM_080844.4 Sequence: HGNPVDDICIAKPRDIPVNPLCIYRSPGKKATEEDGSEQKVPEATNRRVWELSKANSRFATNFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLKQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSDLVSANRLFGDKSLTFNESYQDVSEVVYGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAINELTALVLVNTIYFKGLWKSKFSPENTRKEPFYKVDGQSCPVPMMYQEGKFKYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDELSETMLVVHMPRFRTEDGFSLKEQLQDMGLIDLFSPEKSQLPGIVAGGRDDLYVSDAFHKAFLEVNEEGSEAAASTSVVITGRSLNPNRVTFKANRPFLVLIREVALNTIIFMGRVANPCVN Predict reactive species Full Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Calculated Molecular Weight: 52 kDa Observed Molecular Weight: 52 kDa GenBank Accession Number: NM_080844.4 Gene Symbol: Serpinc1 Gene ID (NCBI): 11905 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P32261 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.