Proteintech, 86346-3-RR, IMPDH2 Recombinant monoclonal antibody

Size: 20ul / 100ul The IMPDH2 (86346-3-RR) by Proteintech is a Recombinant antibody targeting IMPDH2 in WB, ELISA applications with reactivity to human, mouse, rat samples 86346-3-RR targets IMPDH2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HeLa cells, K-562 cells, MCF-7 cells, Jurkat cells, HSC-T6 cells, 4T1 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information IMPDH2, also named as IMPD2, belongs to the IMPDH/GMPR family. It is a rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors. IMPDH2 is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. (PMID:21181270) Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag3632 Product name: Recombinant human IMPDH2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-350 aa of BC012840 Sequence: MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKV Predict reactive species Full Name: IMP (inosine monophosphate) dehydrogenase 2 Calculated Molecular Weight: 514 aa, 56 kDa Observed Molecular Weight: 56 kDa GenBank Accession Number: BC012840 Gene Symbol: IMPDH2 Gene ID (NCBI): 3615 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P12268 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.