Proteintech, 86595-3-RR, PBX3 Recombinant monoclonal antibody

Size: 20ul / 100ul The PBX3 (86595-3-RR) by Proteintech is a Recombinant antibody targeting PBX3 in WB, ELISA applications with reactivity to human, mouse, rat samples 86595-3-RR targets PBX3 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: A431 cells, HeLa cells, fetal human brain tissue, mouse brain tissue, rat brain tissue, mouse lung tissue, rat lung tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information PBX3 is a homeodomain-containing transcription factor of the pre-B cell leukemia (PBX) family, members of which have extensive roles in early development and some adult processes. It plays crucial roles in embryonic development, organogenesis, and cell differentiation by regulating the expression of downstream target genes. Beyond its physiological functions, PBX3 is increasingly recognized for its significant involvement in oncogenesis. It is frequently overexpressed in various malignancies, including leukemias and solid tumors, where it promotes cell proliferation, inhibits apoptosis, enhances invasion and metastasis, and contributes to chemotherapy resistance. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag3239 Product name: Recombinant human PBX3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 19-367 aa of BC016977 Sequence: QLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQSLVKDPKERGSKGSDIQPTSVVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN Predict reactive species Full Name: pre-B-cell leukemia homeobox 3 Calculated Molecular Weight: 434 aa, 47 kDa Observed Molecular Weight: 47-50 kDa GenBank Accession Number: BC016977 Gene Symbol: PBX3 Gene ID (NCBI): 5090 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P40426 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.