Proteintech, 86618-3-RR, PD-ECGF Recombinant monoclonal antibody

Size: 20ul / 100ul The PD-ECGF (86618-3-RR) by Proteintech is a Recombinant antibody targeting PD-ECGF in WB, ELISA applications with reactivity to human samples 86618-3-RR targets PD-ECGF in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: A431 cells, THP-1 cells, OVCAR-3 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Platelet derived endothelial cell growth factor (PD-ECGF), also known as thymidine phosphorylase (TP), induces migration and angiogenesis in endothelial and tumor cells, and was upregulated in various malignancies compared to that in normal tissues. Interestingly, PD-ECGF has dual effect on tumor development and chemotherapy. It could stimulate cancer cell migration and proliferation. On the other hand, some chemotherapeutic agents (5-fluorouracil, capecitabine, etc.) were converted to their active forms through TP enzymes. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag3052 Product name: Recombinant human PD-ECGF protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-297 aa of BC018160 Sequence: MAALMTPGTGAPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPAEGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGA Predict reactive species Full Name: thymidine phosphorylase Calculated Molecular Weight: 482 aa, 50 kDa Observed Molecular Weight: 50 kDa GenBank Accession Number: BC018160 Gene Symbol: Thymidine phosphorylase Gene ID (NCBI): 1890 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P19971 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.