Proteintech, 86794-1-RR, Phospho-AMPK Beta 2 (Ser39) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-AMPK Beta 2 (Ser39) (86794-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-AMPK Beta 2 (Ser39) in WB, ELISA applications with reactivity to human, mouse, rat samples 86794-1-RR targets Phospho-AMPK Beta 2 (Ser39) in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: HeLa cells, A431 cells, mouse skeletal muscle tissue, rat skeletal muscle tissue, λ phosphatase treated HeLa cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information AMPK beta 2 is a regulatory subunit of the AMP-activated protein kinase (AMPK), which is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. AMPK beta 2 may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: protein kinase, AMP-activated, beta 2 non-catalytic subunit Calculated Molecular Weight: 30 kDa Observed Molecular Weight: 34 kDa GenBank Accession Number: BC053610 Gene Symbol: AMPK Beta 2 Gene ID (NCBI): 5565 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O43741 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.