Product Description
Size: 20ul / 100ul
The CCL20/MIP-3 alpha (86916-1-RR) by Proteintech is a Recombinant antibody targeting CCL20/MIP-3 alpha in WB, ELISA applications with reactivity to mouse samples
86916-1-RR targets CCL20/MIP-3 alpha in WB, ELISA applications and shows reactivity with mouse samples.
Tested Applications
Positive WB detected in: Transfected with Mouse CCL20 Transfected HEK-293T cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.
Specification
Tested Reactivity: mouse
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Eg3311 Product name: Recombinant Mouse CCL20/MIP-3 alpha protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 28-96 aa of NM_001159738.1 Sequence: SNYDCCLSYIQTPLPSRAIVGFTRQMADEACDINAIIFHTKKRKSVCADPKQNWVKRAVNLLSLRVKKM Predict reactive species
Full Name: chemokine (C-C motif) ligand 20
Calculated Molecular Weight: 11KD
GenBank Accession Number: NM_001159738.1
Gene Symbol: Ccl20
Gene ID (NCBI): 20297
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: Q642U4
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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