Proteintech, 86947-2-RR, Phospho-LYN (Tyr508) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-LYN (Tyr508) (86947-2-RR) by Proteintech is a Recombinant antibody targeting Phospho-LYN (Tyr508) in WB, ELISA applications with reactivity to human samples 86947-2-RR targets Phospho-LYN (Tyr508) in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: Ramos cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information LYN, also named as JTK8, p53Lyn and p56Lyn, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. The C-terminal tyrosine-508 residue (Tyr-508) in Lyn or the corresponding conserved tyrosine residue in each of the other members of the SFK family is the primary site for regulating tyrosine kinase activity by reversible phosphorylation. Phosphorylation at the tyrosine residue induces a closed conformation that is enzymatically inactive. (PMID: 33004926) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: v-yes-1 Yamaguchi sarcoma viral related oncogene homolog Calculated Molecular Weight: 512 aa, 59 kDa Observed Molecular Weight: 53 kDa, 56 kDa GenBank Accession Number: BC075002 Gene Symbol: LYN Gene ID (NCBI): 4067 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P07948 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.