Proteintech, 86955-1-RR, CST4 Recombinant monoclonal antibody

Size: 20ul / 100ul The CST4 (86955-1-RR) by Proteintech is a Recombinant antibody targeting CST4 in WB, ELISA applications with reactivity to human samples 86955-1-RR targets CST4 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: human saliva Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Cystatins are a family of inhibitors of cysteine peptidases that comprises the salivary cystatins D and S-type (including CST5 and CST4,1,2) and cystatin C-type (CST3) (PMID: 25329717). The D and S-type cystatin have also been detected in seminal plasma, tears, and tracheobronchial fluid but not in other fluids and secretions where cystatin C is found. And the CST4 was expressed in the serous acinar and demilune cells of the human submandibular gland and at lower levels in the serous acini of the parotid gland (PMID:11879580). CST4 specifically combines with cysteine protease to regulate its activity, thus preventing hydrolysis of the extracellular matrix. And some studies propose that CST4 might be a biomarker for gastrointestinal cancer (PMID:29218251; PMID:29636621). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg3098 Product name: recombinant human CST4 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 21-141 aa of NM_001899.2 Sequence: SSSKEENRIIPGGIYDADLNDEWVQRALHFAISEYNKATEDEYYRRPLQVLRAREQTFGGVNYFFDVEVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFEIYEVPWEDRMSLVNSRCQEA Predict reactive species Full Name: cystatin S Calculated Molecular Weight: 16 kDa Observed Molecular Weight: 16 kDa GenBank Accession Number: NM_001899.2 Gene Symbol: Cystatin S Gene ID (NCBI): 1472 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P01036 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.