Proteintech, 87019-1-RR, Phospho-TAU (Ser409) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-TAU (Ser409) (87019-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-TAU (Ser409) in WB, ELISA applications with reactivity to human, mouse samples 87019-1-RR targets Phospho-TAU (Ser409) in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse brain tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information Phosphorylation of tau at Ser409 is an early, disease-specific event in Alzheimer's brain. Catalyzed by PKA, this modification weakens tau-microtubule binding and acts as a molecular switch that initiates tau self-aggregation into paired helical filaments. Consequently, p-Ser409-tau is recognized as an early diagnostic epitope and a potential target for interrupting PKA-driven, oxidative-stress-linked tau pathology. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: microtubule-associated protein tau Calculated Molecular Weight: 37-46, 79-81 kDa Observed Molecular Weight: 45-60 kDa GenBank Accession Number: BC000558 Gene Symbol: TAU Gene ID (NCBI): 4137 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P10636 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.