Proteintech, 87129-2-RR, Phospho-TAK1 (Ser439) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-TAK1 (Ser439) (87129-2-RR) by Proteintech is a Recombinant antibody targeting Phospho-TAK1 (Ser439) in WB, ELISA applications with reactivity to human samples 87129-2-RR targets Phospho-TAK1 (Ser439) in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HEK-293 cells, λ phosphatase treated HEK-293 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information MAP3K7(Mitogen-activated protein kinase kinase kinase 7) is also named TAK1 and belongs to the MAP kinase kinase kinase subfamily. Phospho-TAK1 (Ser439) refers to the phosphorylated form of TAK1 at serine residue 439. TAK1, also known as Transforming Growth Factor-beta activated kinase 1, is a key kinase involved in the regulation of various signaling pathways, including those related to inflammation, immune responses, and cell survival. The phosphorylation of TAK1 at Ser439 is an important post-translational modification that can affect its activity and interaction with other proteins within these pathways. This phosphorylation event is crucial for TAK1's role in signal transduction and its involvement in cellular processes such as the activation of NF-κB and MAPK pathways. It plays a significant role in the activation of downstream signaling cascades that regulate various cellular processes, including cell growth, proliferation, and survival. This antibody is equivalent to Ser412 in mice. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: mitogen-activated protein kinase kinase kinase 7 Calculated Molecular Weight: 67 kDa Observed Molecular Weight: 75-85 kDa GenBank Accession Number: NM_145331 Gene Symbol: TAK1 Gene ID (NCBI): 6885 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O43318 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.