Proteintech, 87358-1-RR, MPDZ/MUPP1 Recombinant monoclonal antibody

Size: 20ul / 100ul The MPDZ/MUPP1 (87358-1-RR) by Proteintech is a Recombinant antibody targeting MPDZ/MUPP1 in WB, ELISA applications with reactivity to human samples 87358-1-RR targets MPDZ/MUPP1 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: SK-N-SH cells, SH-SY5Y cells, A549 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information The PDZ domain is a protein motif that mediates protein-protein interactions. MUPP1(multi-PDZ domain protein-1) has 13 PDZ domains, each containing the structural characteristics of a prototypic PDZ motif, but lacks a catalytic domain. MUPP1 belongs to the PDZ domain protein family and is a structural homologant of PATJ (PALS1-associated tight-linking protein) (PMID: 23880463). MUPP1 is a scaffold protein and plays an important role in cytoskeletal organization, cell polarity, and cell proliferation(PMID: 25662616). Mutations in MUPP1 are associated with congenital hydrocephalus(PMID: 23240096). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg5584 Product name: Recombinant human MPDZ/MUPP1 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 1620-2070 aa of NM_001330637.1 Sequence: CPIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVLS Predict reactive species Full Name: multiple PDZ domain protein Calculated Molecular Weight: 222 kDa Observed Molecular Weight: 250-280 kDa GenBank Accession Number: NM_001330637.1 Gene Symbol: MPDZ Gene ID (NCBI): 8777 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: O75970-1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.