Proteintech, 87408-1-RR, Integrin alpha-8 Recombinant monoclonal antibody

Size: 20ul / 100ul The Integrin alpha-8 (87408-1-RR) by Proteintech is a Recombinant antibody targeting Integrin alpha-8 in WB, IF-P, ELISA applications with reactivity to human, mouse, rat samples 87408-1-RR targets Integrin alpha-8 in WB, IF-P, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse spleen tissue, human kidney tissue, mouse lung tissue, mouse kidney tissue, rat lung tissue, rat spleen tissue, rat kidney tissue Positive IF-P detected in: mouse lung tissue Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Immunofluorescence (IF)-P: IF-P : 1:500-1:2000 Background Information Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. Integrin alpha-8 is a single-pass type I membrane protein that forms a heterodimer with integrin beta-1 to serve as a receptor for RGD-containing matrix molecules (fibronectin, vitronectin, tenascin C, osteopontin, and nephronectin) (PMID: 33000355). Integrin alpha-8 beta-1 plays a critical role in epithelial-mesenchymal interactions and functions in the genesis of kidney and probably of other organs (PMID: 9054500; 19769957). The apparent molecular weight of integrin alpha-8 is larger than the calculated molecular weight of 117 kDa, possibly due to glycosylation (PMID: 7768999). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg10469 Product name: Recombinant mouse ITA8 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011446 of Sequence: \ Predict reactive species Full Name: integrin alpha 8 Calculated Molecular Weight: 117 kDa Observed Molecular Weight: 140 kDa Gene Symbol: Itga8 Gene ID (NCBI): 241226 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: A2ARA8 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.