Proteintech, 87413-2-RR, Phospho-Glucocorticoid receptor (Ser211) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-Glucocorticoid receptor (Ser211) (87413-2-RR) by Proteintech is a Recombinant antibody targeting Phospho-Glucocorticoid receptor (Ser211) in WB, ELISA applications with reactivity to human samples 87413-2-RR targets Phospho-Glucocorticoid receptor (Ser211) in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: dexamethasone treated PC-12 cells Recommended dilution Western Blot (WB): WB : 1:1000-1:4000 Background Information Glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is a receptor for glucocorticoids, which owns a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Ser211 is located within the hinge region of the GR, which connects the DNA-binding domain and the ligand-binding domain. Phosphorylation at Ser211 is crucial for the receptor's transcriptional activity and nuclear translocation. (PMID: 40362450) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Calculated Molecular Weight: 86 kDa Observed Molecular Weight: 95 kDa GenBank Accession Number: BC015610 Gene Symbol: Glucocorticoid receptor Gene ID (NCBI): 2908 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P04150 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.