Proteintech, 87416-2-RR, Integrin beta 4 Recombinant monoclonal antibody

Size: 20ul / 100ul The Integrin beta 4 (87416-2-RR) by Proteintech is a Recombinant antibody targeting Integrin beta 4 in WB, ELISA applications with reactivity to human, mouse, rat samples 87416-2-RR targets Integrin beta 4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: BxPC-3 cells, mouse skin tissue, rat skin tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin beta-4 is predominantly expressed in squamous epithelial cells, endothelial cells, immature thymocytes, Schwann cells, and fibroblasts of the peripheral nervous system (PMID: 28084395). Integrin beta-4 pairs with alpha-6, and the heterodimeric integrin alpha-6/beta-4 is a receptor for laminin. Integrin alpha-6/beta-4 plays a critical structural role in the hemidesmosome of epithelial cells, and also plays a role in the invasive and metastatic phenotype of various cancers. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg10479 Product name: Recombinant human ITB4 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011436 of Sequence: \ Predict reactive species Full Name: integrin, beta 4 Observed Molecular Weight: 200 kDa Gene Symbol: Integrin beta 4 Gene ID (NCBI): 3691 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.