Proteintech, 87424-1-RR, CD61 / Integrin beta 3 Recombinant monoclonal antibody

Size: 20ul / 100ul The CD61 / Integrin beta 3 (87424-1-RR) by Proteintech is a Recombinant antibody targeting CD61 / Integrin beta 3 in WB, ELISA applications with reactivity to mouse, rat samples 87424-1-RR targets CD61 / Integrin beta 3 in WB, ELISA applications and shows reactivity with mouse, rat samples. Tested Applications Positive WB detected in: C2C12 cells, mouse brain tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information Integrin beta-3, also named as CD61 and GPIIIa, is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin beta-3 recognize the sequence R-G-D in a wide array of ligands and the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen which leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Specification Tested Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg10458 Product name: Recombinant mouse ITB3 protein Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-Twin-Strep-Tag Domain: 10011457 of Sequence: \ Predict reactive species Full Name: integrin beta 3 Observed Molecular Weight: 87-130 kDa Gene Symbol: Itgb3 Gene ID (NCBI): 16416 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.