Proteintech, 87524-1-RR, RIC8B Recombinant monoclonal antibody

Size: 20ul / 100ul The RIC8B (87524-1-RR) by Proteintech is a Recombinant antibody targeting RIC8B in WB, ELISA applications with reactivity to human, mouse, rat, pig samples 87524-1-RR targets RIC8B in WB, ELISA applications and shows reactivity with human, mouse, rat, pig samples. Tested Applications Positive WB detected in: HEK-293 cells, mouse cerebellum tissue, mouse brain tissue, rat brain tissue, fetal human brain tissue, pig brain tissue, rat cerebellum tissue Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information Ric8, also known as synembryn, is a guanine nucleotide exchange factor (GEF) that enhances variegated G protein signaling pathways, including Gα(q) and Gα(s) regulation of neurotransmission, Gα(i)-dependent mitotic spindle positioning during (asymmetric) cell division, and Gα(olf)-dependent odorant receptor signaling (PMID: 21467038). In mammals, two Ric8 homologues have been reported (Ric8A and Ric8B). Ric8B is able to potentiate G(s)/G(olf) signaling (PMID: 15829631; 16754875; 20133939). Specification Tested Reactivity: human, mouse, rat, pig Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Ag11888 Product name: Recombinant human RIC8B protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 145-495 aa of BC034220 Sequence: ELQGLPLLTQILESAFSIKWTDEYESAIDHNGPPLSPQETDCAIEALKALFNVTVDSWKVHKESDSHQFRVMAAVLRHCLLIVGPTEDKTEELHSNAVNLLSNVPVSCLDVLICPLTHEETAQEATTLDELPSNKTAEKETVLKNNTMVYNGMNMEAIHVLLNFMEKRIDKGSSYREGLTPVLSLLTECSRAHRNIRKFLKDQVLPPLRDVTNRPEVGSTVRNKLVRLMTHVDLGVKQIAAEFLFVLCKERVDSLLKYTGYGNAAGLLAARGLLAGGRGDNWYSEDEDTDTEEYKNAKPNINLITGHLEEPMPNPIDEMTEEQKEYEAMKLVNMLDKLSRRADVKDLHQDG Predict reactive species Full Name: resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) Calculated Molecular Weight: 495 aa, 61 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC034220 Gene Symbol: RIC8B Gene ID (NCBI): 55188 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9NVN3 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.