Proteintech, 87534-1-RR, Phospho-RPS6KA3 (Ser227) Recombinant monoclonal antibody

Size: 20ul / 100ul The Phospho-RPS6KA3 (Ser227) (87534-1-RR) by Proteintech is a Recombinant antibody targeting Phospho-RPS6KA3 (Ser227) in WB, ELISA applications with reactivity to human samples 87534-1-RR targets Phospho-RPS6KA3 (Ser227) in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: HepG2 cells Recommended dilution Western Blot (WB): WB : 1:2000-1:10000 Background Information Ribosomal S6 Kinase 2 (RSK2), a member of the p90RSK family of serine/threonine kinases, is known to be phosphorylated at Ser227 and Th577 in response to Adriamycin-induced DNA damage. This phosphorylation promotes RSK2 nuclear translocation and enhances RSK2 and Atm interactions in the nuclear fraction, playing an important role in the DNA damage pathway that maintains genomic stability by mediating cell cycle progression and DNA repair. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Peptide Predict reactive species Full Name: ribosomal protein S6 kinase, 90kDa, polypeptide 3 Calculated Molecular Weight: 740 aa, 84 kDa Observed Molecular Weight: 84 kDa GenBank Accession Number: BC096301 Gene Symbol: RSK2 Gene ID (NCBI): 6197 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P51812 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.