Proteintech, 98053-1-RR, Anti-Human IL-2 Rabbit Recombinant Antibody

Size: 100ug The IL-2 (98053-1-RR) by Proteintech is a Recombinant antibody targeting IL-2 in FC (Intra) applications with reactivity to human samples 98053-1-RR targets IL-2 in FC (Intra) applications and shows reactivity with human samples. Tested Applications Positive FC (Intra) detected in: PMA, Ionomycin and Brefeldin A treated human PBMCs Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in 100 μl suspension Background Information Interleukin-2 (IL-2) is a four-helix bundle, type I cytokine that functions as a growth factor for a wide range of leukocytes. In the immune system, IL-2 is essential for immune homeostasis, normal T regulatory cell function, and self-tolerance. It regulates immune cell homeostasis and has been used to treat a range of disorders including cancer and autoimmune disease. IL-2 signals through heterodimerization of the IL-2Rβ and IL-2Rγ receptor subunits (PMID: 25992858, 24907378, 15034008, 17981641). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg0828 Product name: Recombinant Human IL-2 protein (His Tag) Source: mammalian cells -derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 21-153 aa of BC070338 Sequence: APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT Predict reactive species Full Name: interleukin 2 Calculated Molecular Weight: 153 aa, 18 kDa GenBank Accession Number: BC070338 Gene Symbol: IL2 Gene ID (NCBI): 3558 RRID: AB_3672200 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P60568 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2-8°C. Stable for one year after shipment.