Proteintech, 98112-1-RR, Anti-Human TNFRSF9/CD137 Rabbit Recombinant Antibody

Size: 100ug The TNFRSF9/CD137 (98112-1-RR) by Proteintech is a Recombinant antibody targeting TNFRSF9/CD137 in IHC, IF-P, FC applications with reactivity to human samples 98112-1-RR targets TNFRSF9/CD137 in IHC, IF-P, FC applications and shows reactivity with human samples. Tested Applications Positive IHC detected in: human tonsillitis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Positive IF-P detected in: human tonsillitis tissue Positive FC detected in: Con A treated human PBMCs Recommended dilution Immunohistochemistry (IHC): IHC : 1:50-1:500 Immunofluorescence (IF)-P: IF-P : 1:50-1:500 Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: tumor necrosis factor receptor superfamily, member 9 Calculated Molecular Weight: 28 kDa GenBank Accession Number: BC006196 Gene Symbol: TNFRSF9/CD137 Gene ID (NCBI): 3604 RRID: AB_3672259 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q07011 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.