Proteintech, 98122-1-RR, Anti-Mouse CD40 Rabbit Recombinant Antibody

Size: 100ug The CD40 (98122-1-RR) by Proteintech is a Recombinant antibody targeting CD40 in FC applications with reactivity to mouse samples 98122-1-RR targets CD40 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD40, also named as TNFRSF5 and Bp50, is a type I transmembrane protein that belongs to the tumor necrosis factor-R (TNF-R) family (PMID: 10647992). CD40 is expressed on B cells, dendritic cells (DCs), monocytes, platelets, and macrophages as well as by non-hematopoietic cells such as myofibroblasts, fibroblasts, epithelial, and endothelial cells (PMID: 19426221). It is a receptor for TNFSF5/CD40LG. CD40L/CD40 interactions are essential for immunoglobulin (Ig) isotype switching, germinal center formation and the development of B cell memory (PMID: 7516405; 11675497). Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD40 antigen Calculated Molecular Weight: 32 kDa GenBank Accession Number: NM_011611.2 Gene Symbol: Cd40 Gene ID (NCBI): 21939 RRID: AB_3672269 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P27512-1 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.