Proteintech, 98160-1-RR, Anti-Mouse CD27 Rabbit Recombinant Antibody

Size: 100ug The CD27 (98160-1-RR) by Proteintech is a Recombinant antibody targeting CD27 in FC applications with reactivity to mouse samples 98160-1-RR targets CD27 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse splenocytes Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Fusion Protein Predict reactive species Full Name: CD27 antigen Calculated Molecular Weight: 28kDa GenBank Accession Number: NM_001033126.2 Gene Symbol: CD27 Gene ID (NCBI): 21940 RRID: AB_3672303 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P41272 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.