Proteintech, 98200-1-RR, Anti-Human DDR1/CD167a Rabbit Recombinant Antibody

Size: 100ug The DDR1/CD167a (98200-1-RR) by Proteintech is a Recombinant antibody targeting DDR1/CD167a in FC applications with reactivity to human samples 98200-1-RR targets DDR1/CD167a in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: MCF-7 cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information DDR1, or CD167a, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: discoidin domain receptor tyrosine kinase 1 Calculated Molecular Weight: 101 kDa GenBank Accession Number: NM_001297654 Gene Symbol: DDR1 Gene ID (NCBI): 780 RRID: AB_3672333 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: Q08345-1 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.