Proteintech, 98216-1-RR, Anti-Human IL-13Ra1/CD213a1 Rabbit Recombinant Antibody

Size: 100ug The IL-13Ra1/CD213a1 (98216-1-RR) by Proteintech is a Recombinant antibody targeting IL-13Ra1/CD213a1 in FC applications with reactivity to human samples 98216-1-RR targets IL-13Ra1/CD213a1 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: MCF-7 cells Recommended dilution Flow Cytometry (FC): FC : 0.13 ug per 10^6 cells in 100 μl suspension Background Information IL-13 is an immunoregulatory cytokine secreted predominantly by activated T-helper 2 (Th2) cells and performs multiple functions through a complex receptor system comprised of IL-4Rα and two IL-13 binding proteins, IL-13Rα1 and IL-13Rα2 (PMID: 12704343). IL-13Rα1 is a glycosylated transmembrane protein (PMID: 10856136; 9723655). IL-13Rα1 is expressed on a wide range of cells including B cells, monocytes, macrophages, basophils, mast cells, and endothelial cells (PMID: 10856136; 31866859). IL-13 binding to the IL-4Rα/IL-13Rα1 complex leads to activation of JAK1, JAK2, and TYK2 and subsequent phosphorylation of STAT6 and STAT3 (PMID: 31866859). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: interleukin 13 receptor, alpha 1 Calculated Molecular Weight: 49 kDa GenBank Accession Number: BC009960 Gene Symbol: IL-13Rα1 Gene ID (NCBI): 3597 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purfication UNIPROT ID: P78552 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.